Selected Publications
Dr. Gregg Fields' Selected Publications
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Dr. Gregg Fields' Selected Publications
Navdeep B. Malkar and Gregg B. Fields. Synthesis of Nα-(fluoren-9-ylmethoxycarbonyl)-Nε-[(7-methoxycoumarin-4-yl)acetyl]-L-lysine for use in solid-phase synthesis of fluorogenic substrates. Lett. Peptide Sci., 263-267 (2001).
Jeffrey A. Borgia, Navdeep B. Malkar, Husam U. Abbassi, and Gregg B. Fields. Difficulties Encountered During Glycopeptide Syntheses. J. Biomolecular Techniques 12, 44-68 (2001).
W. Barry Edwards, Carolyn J. Anderson, Gregg B. Fields, and Michael J. Welch. Evaluation of Radiolabeled Type IV Collagen Fragments as Tumor Imaging Agents. Bioconjugate Chem. 12, 1057-1065 (2001).
Angela K. Dillow, Sarah E. Ochsenhirt, James B. McCarthy, Gregg B. Fields, and Matthew Tirrell. Adhesion of α5β1 receptors to biomimetic substrates constructed from peptide amphiphiles. Biomaterials 22, 1493-1505 (2001).
Navdeep B. Malkar, Janelle L. Lauer-Fields, Jeffrey A. Borgia, and Gregg B. Fields. Modulation of Triple-Helical Stability and Subsequent Melanoma Cellular Responses by Single-Site Substitution of Fluoroproline Derivatives. Biochemistry 41, 6054-6064 (2002).
Janelle L. Lauer-Fields and Gregg B. Fields. Triple-Helical Peptide Analysis of Collagenolytic Protease Activity. Biol. Chem. 383, 1095-1105 (2002).
Janelle L. Lauer-Fields, Darius Juska, and Gregg B. Fields. Matrix Metalloproteinases and Collagen Catabolism. Biopolymers (Peptide Science) 66, 19-32 (2002).
Gregg B. Fields. Protease-activated drug delivery. Exp. Opin. Ther. Patents 13, 125-127 (2003).
Janelle L. Lauer-Fields, Navdeep B. Malkar, Gérard Richet, Karlheinz Drauz, and Gregg B. Fields. Melanoma Cell CD44 Interaction with the α1(IV)1263-1277 Region from Basement Membrane Collagen is Modulated by Ligand Glycoslyation. J. Biol. Chem. 278, 14321-14330 (2003).
Janelle L. Lauer-Fields, Thilaka Sritharan, M. Sharon Stack, Hideaki Nagase, and Gregg B. Fields. Selective Hydrolysis of Triple-Helical Substrates by Matrix Metalloproteinase-2 and -9. J. Biol. Chem. 278, 18140-18145 (2003).
Navdeep B. Malkar, Janelle L. Lauer-Fields, Darius Juska, and Gregg B. Fields. Characterization of Peptide-Amphiphiles Possessing Cellular Activation Sequences. Biomacromolecules 4, 518-528 (2003).
M.P. Lütolf, J.L. Lauer-Fields, H. Schmoekel, A.T. Metters, F.E. Weber, G.B. Fields, and J.A. Hubbell. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell invasion characteristics. Proc. Natl. Acad. Sci. USA 100, 5413-5418 (2003).
Frank Marí and Gregg B. Fields. Conopeptides: Unique pharmacological agents that challenge current peptide methodologies. Chim. Oggi/Chemistry Today 21(6), 43-48 (2003).
Shawn M. Sweeney, Gloria DiLullo, Simon J. Slater, José Martinez, Renato V. Iozzo, Janelle L. Lauer-Fields, Gregg B. Fields, and James D. San Antonio. Angiogenesis in Collagen I Requires α2β1 Ligation of a GFP*GER Sequence and Possibly p38 MAPK Activation and Focal Adhesion Disassembly. J. Biol. Chem. 278, 30516-30524 (2003).
Diane Baronas-Lowell, Janelle L. Lauer-Fields, and Gregg B. Fields. Defining the roles of collagen and collagen-like proteins within the proteome. J. Liq. Chromatogr. Rel. Technol. 26, 2225-2254 (2003).
Janelle L. Lauer-Fields, Péter Kele, Guodong Sui, Hideaki Nagase, Roger M. Leblanc, and Gregg B. Fields. Analysis of matrix metalloproteinase activity using triple-helical substrates incorporating fluorogenic L- or D-amino acids. Anal. Biochem. 321, 105-115 (2003).
Diane Baronas-Lowell, Janelle L. Lauer-Fields and Gregg B. Fields. Induction of Endothelial Cell Activation by a Triple-Helical α2β1 Integrin Ligand Derived from Type I Collagen α1(I)496-507. J. Biol. Chem. 279, 952-962 (2004).
Zhenqiang Li, Yoshiyuki Yasuda, Weije Li, Matthew Bogyo, Norman Katz, Ronald E. Gordon, Gregg B. Fields, and Dieter Brömme. Regulation of Collagenase Activities of Human Cathepsins by Glycosaminoglycans. J. Biol. Chem. 279, 5470-5479 (2004).
Douglas R. Hurst, Martin A. Schwartz, Mohammad A. Ghaffari, Yonghao Jin, Harald Tschesche, Gregg B. Fields, and Qing-Xiang Amy Sang. Catalytic- and Ecto-domains of Membrane Type 1-Matrix Metalloproteinase have Similar Inhibition Profiles but Distinct Endopeptidase Activities. Biochem. J. 377, 775-779 (2004).
Xiaoping Xu, Yao Wang, Janelle L. Lauer-Fields, Gregg B. Fields, and Bjorn Steffensen. Contributions of the MMP-2 Collagen Binding Domain to Gelatin Cleavage: Substrate Binding via the Collagen Binding Domain is Required for MMP-2 Degradation of Gelatin But Not Short Peptides. Matrix Biol. 23, 171-181 (2004).
Linda Chung, Deendayal Dinakarpandian, Naoto Yoshida, Janelle L. Lauer-Fields, Gregg B. Fields, Robert Visse, and Hideaki Nagase. Collagenase Unwinds Triple Helical Collagen Prior To Peptide Bond Hydrolysis. EMBO J. 23, 3020-3030 (2004).
Dmitriy Minond, Janelle L. Lauer-Fields, Hideaki Nagase, and Gregg B. Fields. Matrix Metalloproteinase Triple-Helical Peptidase Activities are Differentially Regulated by Substrate Stability. Biochemistry 43, 11474-11481 (2004).
Diane Baronas-Lowell, Janelle L. Lauer-Fields, Jeffrey A. Borgia, Gian Franco Sferrazza, Mohammad Al-Ghoul, Dmitriy Minond, and Gregg B. Fields. Differential Modulation of Human Melanoma Cell Metalloproteinase Expression by α2β1 Integrin and CD44 Triple-Helical Ligands Derived from Type IV Collagen. J. Biol. Chem. 279, 43503-43513 (2004).
Janelle L. Lauer-Fields, Hideaki Nagase, and Gregg B. Fields. Development of a Solid-Phase Assay for Analysis of Matrix Metalloproteinase Activity. J. Biomolecular Techniques 15, 305-316 (2004).
M. Cudic, J.L. Lauer-Fields, and G.B. Fields. Improved synthesis of 5-hydroxylysine (Hyl) derivatives. J. Peptide Res. 65, 272-283 (2005).
Katarzyna Pisarewicz, David Mora, Fred C. Pflueger, Gregg B. Fields, and Frank Mari. Polypeptide Chains Containing D-y-Hydroxyvaline. J. Am. Chem. Soc. 127, 6207-6215 (2005).
Carolina Möller, Sanaz Rahmankhah, Janelle Lauer-Fields, Jose Bubis, Gregg B. Fields, and Frank Marí. A Novel Conotoxin Framework with a Helix-Loop-Helix (Cs α/α) Fold. Biochemistry 44, 15986-15996 (2005).
Janelle L. Lauer-Fields, Dmitriy Minond, Keith Brew, and Gregg B. Fields. Application of Topologically Constrained Mini-Proteins as Ligands, Substrates, and Inhibitors. Methods Mol. Biol., in press (2006).
Diane Baronas-Lowell, Janelle L. Lauer-Fields, Mohammad Al-Ghoul, and Gregg B. Fields. Proteolytic Profiling of the Extracellular Matrix Degradome. Methods Mol. Biol., in press (2006).
Evonne M. Rezler, David R. Khan, Raymond Tu, Matthew Tirrell, and Gregg B. Fields. Peptide-Mediated Targeting of Liposomes to Tumor Cells. Methods Mol. Biol., in press (2006).
Janelle L. Lauer-Fields, Thilaka Sritharan, Masahide Kashiwagi, Hideaki Nagase, and Gregg B. Fields. Substrate Conformation Modulates Aggrecanase (ADAMTS-4) Affinity and Sequence Specificity: Suggestion of a Common Topological Specificity of Functionally Diverse Proteases. J. Biol. Chem. 281, in press (2006).
Dmitriy Minond, Janelle L. Lauer-Fields, Mare Cudic, Christopher M. Overall, Duanqing Pei, Keith Brew, Robert Visse, Hideaki Nagase, and Gregg B. Fields. The Roles of Substrate Thermal Stability and P2 and P1’ Subsite Identity on Matrix Metalloproteinase Triple-Helical Peptidase Activity and Collagen Specificity. J. Biol. Chem. 281, in press (2006).
Dmitriy Minond, Janelle L. Lauer-Fields, Mare Cudic, Christopher M. Overall, Duanqing Pei, Keith Brew, Marcia L. Moss, and Gregg B. Fields. Differentiation of Secreted and Membrane-Type Matrix Metalloproteinase Activities Based on Substitutions and Interruptions of Triple-Helical Sequences. Biochemistry, revised (2006).
Evonne M. Rezler, David R. Khan, Janelle L. Lauer-Fields, Mare Cudic, Diane Baronas-Lowell, and Gregg B. Fields. Targeted drug delivery utilizing protein-like molecular architecture. J. Am. Chem. Soc., submitted (2006).
Navdeep B. Malkar and Gregg B. Fields. Synthesis of Na-(fluoren-9-ylmethoxycarbonyl)-Ne-[(7-methoxycoumarin-4-yl)acetyl]-L-lysine for use in solid-phase synthesis of fluorogenic substrates. Lett. Peptide Sci., in press (2001).
Janelle L. Lauer-Fields, Todd Broder, Thilaka Sritharan, Linda Chung, Hideaki Nagase, and Gregg B. Fields. Kinetic Analysis of Matrix Metalloproteinase Activity Using Fluorogenic Triple-Helical Substrates. Biochemistry, Vol 40, No.19, (2001).
Linda Chung, Ken-ichi Shimokawa, Deendayal Dinakarpandian, Frank Grams, Gregg B. Fields, and Hideaki Nagase. Mapping the RWTNNFREY (183-191) Region As a Critical Segment of Matrix Metalloproteinase 1 For the Expression of Collagenolytic Activity. J. Biol. Chem. 275, 29610-29617 (2000).
Navdeep B. Malkar, Janelle L. Lauer-Fields, and Gregg B. Fields. Convenient Synthesis of Glycosylated Hydroxylysine Derivatives for Use in Solid-Phase Synthesis. Tetrahedron Lett. 41, 1137-1140 (2000).
Janelle L. Lauer-Fields and Gregg B. Fields. Matrix metalloproteinase inhibitors and cancer. Exp. Opin. Ther. Patents 10, 1873-1884 (2000).
Jeffrey A. Borgia and Gregg B. Fields. Chemical synthesis of proteins. Trends Biotech. 18, 243-251 (2000).
Janelle L. Lauer-Fields, Hideaki Nagase, and Gregg B. Fields. Use of Edman degradation sequence analysis and matrix-assisted laser desorption/ionization mass spectrometry in designing substrates for matrix metalloproteinases. J. Chromatogr. A 890, 117-125 (2000).
Pilar Forns, Janelle L. Lauer-Fields, Su Gao, and Gregg B. Fields. Induction of Protein-Like Molecular Architecture by Monoalkyl Hydrocarbon Chains. Biopolymers 54, 531-546 (2000).
Pilar Forns and Gregg B. Fields. Peptide-Amphiphile Induction of a-Helical Structures. Polymer Preprints 41(2), 1152-1153 (2000).
Janelle L. Lauer-Fields, Kathleen A. Tuzinski, Ken-ichi Shimokawa, Hideaki Nagase, and Gregg B. Fields. Hydrolysis of Triple-Helical Collagen Peptide Models by Matrix Metalloproteinases. J. Biol. Chem.275, 13282-13290 (2000).Yoav Dori, Havazelet Bianco-Peled, Sushil K. Satija, Gregg B. Fields, James B. McCarthy, and Matthew Tirrell. Ligand accessibility as a means to control cell response to bioactive bilayer membranes. J. Biomed. Mater. Res. 50, 75-81 (2000).
Teika Pakalns, Kraig L. Haverstick, Gregg B. Fields, James B. McCarthy, Daniel L. Mooradian, and Matthew Tirrell. Cellular recognition of synthetic peptide amphiphiles in self-assembled monolayer films. Biomaterials20, 2265-2279 (1999).
Gregg B. Fields. Polymer-platinum compounds. Exp. Opin. Ther. Patents 9, 661-662 (1999).
Gregg B. Fields. Induction of Protein-like Molecular Architecture by Self-assembly Processes. Bioorg. Med. Chem. 7, 75-81 (1999).
Ying-Ching Yu, Vikram Roontga, Vladimir A. Daragan, Kevin H. Mayo, Matthew Tirrell, and Gregg B. Fields. Structure and Dynamics of Peptide-Amphiphiles Incorporating Triple-Helical Protein-Like Molecular Architecture. Biochemistry38, 1659-1668 (1999).
Ying-Ching Yu, Matthew Tirrell, and Gregg B. Fields. Minimal Lipidation Stabilizes Protein-Like Molecular Architecture. J. Am. Chem. Soc. 120, 9979-9987 (1998).
S. Setty, Y. Kim, G.B. Fields, D.O. Clegg, E.A. Wayner, and E.C. Tsilibary. Interactions of Type IV Collagen and Its Domains With Human Mesangial Cells. J. Biol. Chem. 273, 12244-12249 (1998).
Gregg B. Fields. Integrins: cell adhesion molecules in cancer. Exp. Opin. Ther. Patents 8, 633-644 (1998).
Janelle L. Lauer, Christi M. Gendron, and Gregg B. Fields. Effect of Ligand Conformation on Melanoma Cell a3b1 Integrin-Mediated Signal Transduction Events: Implications For A Collagen Structural Modulation Mechanism Of Tumor Cell Invasion. Biochemistry37, 5279-5287 (1998).
Shawn M. Sweeney, Cynthia A. Guy, Gregg B. Fields, and James D. San Antonio. Defining the domains of type I collagen involved in heparin-binding and endothelial tube formation. Proc. Natl. Acad. Sci. USA 95, 7275-7280 (1998).
Gregg B. Fields, Janelle L. Lauer, Yoav Dori, Pilar Forns, Ying-Ching Yu, and Matthew Tirrell. Proteinlike Molecular Architecture: Biomaterial Applications for Inducing Cellular Receptor Binding and Signal Transduction. Biopolymers47, 143-151 (1998).
Changfen Li, James B. McCarthy, Leo T. Furcht, and Gregg B. Fields. An All-D Peptide Model of a1(IV)531-543 From Type IV Collagen Binds the a3b1 Integrin and Mediates Melanoma Cell Adhesion, Spreading, and Motility. Biochemistry 36, 15404-15410 (1997).
W.B. Edwards, C.J. Anderson, C.G. Fields, G.B. Fields, and M.J. Welch. Evaluation of Cu-64-Labeled Segments of Type IV Collagen as Tumor Imaging Agents. J. Labelled Compds. Radiopharm. 150, 389-390 (1997).
Curtis B. Herbert, Terri L. McLernon, Claire L. Hypolite, Derek N. Adams, Lana Pikus, C.-C. Huang, Gregg B. Fields, Paul C. Letourneau, Mark D. Distefano, and Wei-Shou Hu. Micropatterning gradients and controlling surface densities of photoactivatable biomolecules on self-assembled monolayers of oligo(ethylene glycol) alkanethiolates. Chem. Biol. 4, 731-737 (1997).
Janelle L. Lauer, Leo T. Furcht, and Gregg B. Fields. Inhibition of Melanoma Cell Binding to Type IV Collagen by Analogs of Cell Adhesion Regulator. J. Med. Chem. 40, 3077-3084 (1997).
Anissa S.H. Chan, James L. Mobley, Gregg B. Fields, and Yoji Shimizu. CD7-Mediated Regulation of Integrin Adhesiveness on Resting Human T Cells Involves Tyrosine Phosphorylation-Dependent Activation of Phosphatidylinositol 3-Kinase. J. Immunol. 159, 934-942 (1997).
Ruth Hogue Angeletti, Lynda F. Bonewald, and Gregg B. Fields. Six Year Study of Peptide Synthesis. Meth. Enzymol. 289, 697-717 (1997).
Janelle L. Lauer and Gregg B. Fields. In Vitro Incorporation of Synthetic Peptides Into Cells. Meth. Enzymol. 289, 564-571 (1997).
Ying-Ching Yu, Teika Pakalns, Yoav Dori, James B. McCarthy, Matthew Tirrell, and Gregg B. Fields. Construction of Biologically Active Protein Molecular Architecture Using Self-Assembling Peptide-Amphiphiles. Meth. Enzymol.289, 571-587 (1997).
Cynthia A. Guy and Gregg B. Fields. Trifluoroacetic Acid Cleavage and Deprotection of Resin-Bound Peptides Following Synthesis by Fmoc Chemistry. Meth. Enzymol. 289, 67-83 (1997).
Gregg B. Fields. Mass-Spectrometric Approaches for DNA-Based Genetic Screening. Clin. Chem. 43, 1108-1109 (1997).
Vladimir A. Daragan, Elena E. Ilyina, Cynthia G. Fields, Gregg B. Fields, and Kevin H. Mayo. Backbone and Side-Chain Dynamics of Residues in a Partially Folded b-Sheet Peptide from Platelet Factor 4. Protein Sci. 6, 355-363 (1997).
Ying-Ching Yu, Peter Berndt, Matthew Tirrell, and Gregg B. Fields. Self-Assembling Amphiphiles for Construction of Protein Molecular Architecture. J. Am. Chem. Soc. 118, 12515-12520 (1996).
Hideaki Nagase and Gregg B. Fields. Human Matrix Metalloproteinase Specificity Studies Using Collagen Sequence-Based Synthetic Peptides. Biopolymers (Peptide Science) 40, 399-416 (1996).
Gregg B. Fields and Darwin J. Prockop. Perspectives on the Synthesis & Application of Triple-Helical, Collagen-Model Peptides. Biopolymers (Peptide Science) 40, 345-357 (1996).
Joseph B. Huebsch, Gregg B. Fields, Thomas G. Triebes, and Daniel L. Mooradian. Photoreactive analog of peptide FN-C/H-V from the carboxy-terminal heparin-binding domains of fibronectin supports endothelial cell adhesion and spreading on biomaterial surfaces. J. Biomed. Mat. Res.31, 555-567 (1996).
Beate Grab, Andrew J. Miles, Leo T. Furcht, and Gregg B. Fields. Promotion of Fibroblast Adhesion by Triple-Helical Peptide Models of Type I Collagen-Derived Sequences. J. Biol. Chem. 271, 12234-12240 (1996).
Cynthia G. Fields, Beate Grab, Janelle L. Lauer, Andrew J. Miles, Ying-Ching Yu, and Gregg B. Fields. Solid-phase synthesis of triple-helical Collagen-model peptides. Lett. Peptide Sci. 3, 3-16 (1996).
Jennifer R. Knutson, Joji Iida, Gregg B. Fields, and James B. McCarthy. CD44/Chondroitin Sulfate Proteoglycan and a2b1 Integrin Mediate Human Melanoma Cell Migration on Type IV Collagen and Invasion of Basement Membranes. Mol. Biol. Cell 7, 383-396 (1996).
Andrew J. Miles, Jennifer R. Knutson, Amy P.N. Skubitz, Leo T. Furcht, James B. McCarthy, and Gregg B. Fields. A Peptide Model of Basement Membrane Collagen a1(IV)531-543 Binds the a3b1 Integrin. J. Biol. Chem. 270, 29047-29050 (1995).
Cynthia G. Fields, Beate Grab, Janelle L. Lauer, and Gregg B. Fields. Purification and Analysis of Synthetic, Triple-Helical "Minicollagens" by Reversed-Phase High-Performance Liquid Chromatography. Anal. Biochem.231, 57-64 (1995).
Peter Berndt, Gregg B. Fields, and Matthew Tirrell. Synthetic Lipidation of Peptides and Amino Acids: Monolayer Structure and Properties. J. Am. Chem. Soc. 117, 9515-9522 (1995).
Leo T. Furcht, Amy P.N. Skubitz, and Gregg B. Fields. Metalloproteinases and Tumor Cell Invasion - Response. Lab. Invest. 72, 125 (1995). 32. Gregg B. Fields. The Collagen Triple-Helix: Correlation of Conformation with Biological Activities. Connect. Tissue Res. 31, 235-243 (1995).
Janelle L. Lauer, Cynthia G. Fields, and Gregg B. Fields. Sequence Dependence of Aspartimide Formation During 9-Fluorenylmethoxycarbonyl Solid-Phase Peptide Synthesis. Lett. Peptide Sci. 1, 197-205 (1995).
Andrew J. Miles, Amy P.N. Skubitz, Leo T. Furcht, and Gregg B. Fields. Promotion of Cell Adhesion by Single-stranded and Triple-helical Peptide Models of Basement Membrane Collagen a1(IV)531-543: Evidence for Conformationally Dependent and Conformationally Independent Type IV Collagen Cell Adhesion Sites. J. Biol. Chem. 269, 30939-30945 (1994).
W. Barry Edwards, Cynthia G. Fields, Carolyn J. Anderson, Tammy S. Pajeau, Michael J. Welch, and Gregg B. Fields. Generally Applicable, Convenient Solid-Phase Synthesis and Receptor Affinities of Octreotide Analogs. J. Med. Chem. 37, 3749-3757 (1994).
Hideaki Nagase, Cynthia G. Fields, and Gregg B. Fields. Design and Characterization of a Fluorogenic Substrate Selectively Hydrolyzed by Stromelysin 1 (Matrix Metalloproteinase-3). J. Biol. Chem.269, 20952-20957 (1994).
Leo T. Furcht, Amy P.N. Skubitz, and Gregg B. Fields. Tumor Cell Invasion, Matrix Metalloproteinases, and the Dogma. Lab. Invest.70, 781-783 (1994).
Gundu H.R. Rao, Cynthia G. Fields, James G. White, and Gregg B. Fields. Promotion of Human Platelet Adhesion and Aggregation by a Synthetic, Triple-helical "Mini-collagen". J. Biol. Chem.269, 13899-13903 (1994).
Liana Harvath, Nicole E. Brownson, Gregg B. Fields, and Amy P.N. Skubitz. Laminin Peptides Stimulate Human Neutrophil Motility. J. Immunol. 152, 5447-5456 (1994).
W.B. Edwards, C.J. Anderson, M.J. Welch, C.G. Fields, and G.B. Fields. The Synthesis of DTPA-D-Phe1-Octreotide by Solid-Phase Synthesis. J. Labelled Compds. Radiopharm. 35, 359-361 (1994).
Cynthia G. Fields and Gregg B. Fields. Minimization of Tryptophan Alkylation Following 9-Fluorenylmethoxycarbonyl Solid-Phase Peptide Synthesis. Tetrahedron Lett. 34, 6661-6664 (1993).
Cynthia G. Fields, Christine M. Lovdahl, Andrew J. Miles, Vickie L. Matthias Hagen, and Gregg B. Fields. Solid-Phase Synthesis and Stability of Triple-Helical Peptides Incorporating Native Collagen Sequences. Biopolymers 33, 1695-1707 (1993).
W. Dale Branton, Marla S. Rudnick, Yi Zhou, Eric D. Eccleston, Gregg B. Fields, and Larry D. Bowers. Fatty Acylated Toxin Structure. Nature 365, 496-497 (1993).
W. Dale Branton, Cynthia G. Fields, Vickie L. VanDrisse, and Gregg B. Fields. Solid-Phase Synthesis of O-Palmitoylated Peptides. Tetrahedron Lett. 34, 4885-4888 (1993).
Gregg B. Fields. Synthetic Peptides and Tumor Cell Metastasis. Peptide Res. 6, 115-120 (1993).
Cynthia G. Fields, Daniel J. Mickelson, Sandra L. Drake, James B. McCarthy, and Gregg B. Fields. Melanoma Cell Adhesion and Spreading Activities of a Synthetic 124-Residue Triple-helical "Mini-collagen." J. Biol. Chem. 268, 14153-14160 (1993).
Cynthia G. Fields, Vickie L. VanDrisse, and Gregg B. Fields. Edman Degradation Sequence Analysis of Resin-Bound Peptides Synthesized by 9-Fluorenylmethoxycarbonyl Chemistry. Peptide Res. 6, 39-47 (1993).
Sarah J. Netzel-Arnett, Gregg B. Fields, Hideaki Nagase, Ko Suzuki, William G.I. Moore, Henning Birkedal-Hansen, and Harold E. Van Wart. Comparative Sequence Specificities of Human Fibroblast and Neutrophil Matrix Metalloproteinases. Matrix: Coll. Rel. Res., Suppl. 1, 74-75 (1992).
Umesh B. Goli, Gregg B. Fields, and Harold E. Van Wart. Synthetic Triple Helical Models for the Collagen Cleavage Site in Interstitial Collagens. Matrix: Coll. Rel. Res., Suppl. 1, 71-72 (1992).
Gregg B. Fields and Harold E. Van Wart. Unique Features of the Tissue Collagenase Cleavage Site in Interstitial Collagens. Matrix: Coll. Rel. Res., Suppl. 1, 68-70 (1992).
Cynthia G. Fields, Albert Loffet, Steven A. Kates, and Gregg B. Fields. The Development of High-Performance Liquid Chromatographic Analysis of Allyl and Allyloxycarbonyl Side-Chain-Protected Phenylthiohydantoin-Amino Acids. Anal. Biochem. 203, 245-251 (1992).
Gregg B. Fields, Darwin O.V. Alonso, Dirk Stigter, and Ken A. Dill. Theory for the Aggregation of Proteins and Copolymers. J. Phys. Chem. 96, 3974-3981 (1992).
Sarah Netzel-Arnett, Gregg B. Fields, Henning Birkedal-Hansen, and Harold E. Van Wart. Sequence Specificities of Human Fibroblast and Neutrophil Collagenases. J. Biol. Chem. 266, 6747-6755, 21326 (1991).
Gregg B. Fields. A Model For Interstitial Collagen Catabolism by Mammalian Collagenases. J. Theor. Biol. 153, 585-602 (1991).
Gregg B. Fields and Cynthia G. Fields. Solvation Effects in Solid-Phase Peptide Synthesis. J. Am. Chem. Soc. 113, 4202-4207 (1991). Supplementary material: 7 pages.
David S. King, Cynthia G. Fields, and Gregg B. Fields. A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. Int. J. Peptide Protein Res. 36, 255-266 (1990).
Gregg B. Fields, Sarah J. Netzel-Arnett, Lester J. Windsor, Jeffrey A. Engler, Henning Birkedal-Hansen, and Harold E. Van Wart. The Proteolytic Activities of Human Fibroblast Collagenase: Hydrolysis of a Broad Range of Substrates at a Single Active Site. Biochemistry 29, 6670-6677 (1990).
Gregg B. Fields and Richard L. Noble. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.Int. J. Peptide Protein Res. 35, 161-214 (1990).
Cynthia G. Fields, Gregg B. Fields, Richard L. Noble, and T.A.Cross. Solid phase peptide synthesis of 15N-gramicidins A, B, and C and high performance liquid chromatographic purification. Int. J. Peptide Protein Res. 33, 298-303 (1989).
Gregg B. Fields, Cynthia G. Fields, Hank Henricks, and Tim A. Cross. Reversed Phase Purification of Synthetic Gramicidins. Chromatogram 9(2), 6-8 (1988).
Gregg B. Fields, Cynthia G. Fields, Jonathan Petefish, Harold E. Van Wart, and T.A. Cross. Solid-phase peptide synthesis and solid state NMR spectroscopy of [15N-Ala3]-Val1-gramicidinA. Proc. Natl. Acad. Sci. USA 85, 1384-1388 (1988).
Gregg B. Fields, Harold E. Van Wart, and Henning Birkedal-Hansen. Sequence Specificity of Human Skin Fibroblast Collagenase: Evidence For the Role of Collagen Structure in Determining the Collagenase Cleavage Site. J. Biol. Chem. 262, 6221-6226 (1987).
BOOKS AND BOOK CHAPTERS - REVIEWS
Gregg B. Fields, Ruth H. Angeletti, Lynda F. Bonewald, William T. Moore, Alan J. Smith, John T. Stults, and Lynn C. Williams. Correlation of Cleavage Techniques With Side-Reactions Following Solid-Phase Peptide Synthesis. In "Techniques in Protein Chemistry VI" (J.W. Crabb, Ed.), Academic Press, Orlando, FL, pp. 539-546 (1995).
Cynthia G. Fields and Gregg B. Fields. Chapter 3: Solvents for Solid-Phase Peptide Synthesis. In "Methods in Molecular Biology, Vol. 35: Peptide Synthesis Protocols" (M.W. Pennington and B.M. Dunn, Eds.), Humana Press, Totowa, NJ, pp. 29-40 (1994).
Gregg B. Fields. Chapter 2: Methods for Removing the Fmoc Group. In "Methods in Molecular Biology, Vol. 35: Peptide Synthesis Protocols" (M.W. Pennington and B.M. Dunn, Eds.), Humana Press, Totowa, NJ, pp. 17-27 (1994).
Gregg B. Fields, Ruth H. Angeletti, Steven A. Carr, Alan J. Smith, John T. Stults, Lynn C. Williams, and Janis D. Young. Variable Success of Peptide-Resin Cleavage and Deprotection Following Solid-Phase Synthesis. In "Techniques in Protein Chemistry V" (J.W. Crabb, Ed.), Academic Press, Orlando, FL, pp. 501-507 (1994).
Gregg B. Fields, Steven A. Carr, Daniel R. Marshak, Alan J. Smith, John T. Stults, Lynn C. Williams, Ken R. Williams, and Janis D. Young. Evaluation of Peptide Synthesis As Practiced in 53 Different Laboratories. In "Techniques in Protein Chemistry IV" (R.H. Angeletti, Ed.), Academic Press, Orlando, FL, pp. 229-238 (1993).
Gregg B. Fields, Zhenping Tian, and George Barany. Principles and Practice of Solid-Phase Peptide Synthesis. In "Synthetic Peptides: A User's Guide" (G.A. Grant, Ed.), W.H. Freeman & Co., New York, pp. 77-183 (1992).
Gregg B. Fields. The Application of Solid Phase Peptide Synthesis to the Study of Structure-Function Relationships in the Collagen-Collagenase System. Ph.D. Thesis, Florida State University, Tallahassee, FL, 213 pages, 1988.
Janelle L. Lauer, "Agonist Induced Contraction is Linked to Protein Tyrosine Phosphorylation in Smooth Muscle," M.S. Dissertation, University of Minnesota (1994).
Joseph DiSalvo, Lori Semenchuk, and Janelle L. Lauer. Vanadate-Induced Contraction of Smooth Muscle and Enhanced Protein Tyrosine Phosphorylation, Arch. Biochem. Biophys. 304, 386-391 (1993).
Joseph DiSalvo, Karen Kolquist, Janelle L. Lauer, and Lori Semenchuk. Vanadate-Induced Contraction of Smooth Muscle is Associated with Protein Tyrosine Phosphorylation. FASEB J. 6 (1992). 76th Annual Federation of American Societies for Experimental Biology Meeting, 1992.