Research
1. Development and redevelopment of new courses for the Undergraduate Chemistry curriculum designed to
facilitate a deeper understanding of foundational concepts via novel technologies and pedagogical approaches
that facilitate student learning.
2. Development and redevelopment of the General Chemistry I Lab experiments to improve both student
enthusiasm and comprehension of abstract theory through valuable hands-on experimentation.
3. Participates in the development of a WAC-based writing-intensive course for the Undergraduate
Chemistry curriculum, Advanced General Chemistry II course
(CHM 2051), that focuses on the use of writing to facilitate critical thinking skills
while concomitantly preparing the next generation of scientists to produce academic-level
writing suitable for publication.
Recent Publications
K. Kasdorf and Dennis C. Liotta "Development of a Complexed Chiral Auxiliary for the Asymmetric Cyclopropanation of
Allylic Alcohols" CHEMTRACTS 1997, 10, 533-535.
A. G. M. Barrett, W. W. Doubleday, D. Hamprecht, K. Kasdorf, G. J. Tustin, A. J. P. White and D. J. Williams "Assembly of
the Antifungal Agent FR-900848 and the CETP inhibitor U-106305: Studies on Remarkable Multicyclopropane Natural Products" Chem. Commun.
1997, 1693-1700.
A. G. M. Barrett, W. W. Doubleday, D. Hamprecht, K. Kasdorf, and G. J. Tustin "Recent Advances in the Synthesis of Antifungal
Agents" Pure Appl. Chem. 1997, 69, 383-388.
A. G. M. Barrett and K. Kasdorf "Total Synthesis of the Pentacyclopropane Antifungal Agent FR-900848" J. Am. Chem.
Soc. 1996, 118, 11030-11037.
A. G. M. Barrett, W. W. Doubleday, K. Kasdorf, M. Pena, G. J. Tustin and J. A. Willardsen "Recent Advances in the
Synthesis of Bioactive Natural Products" J. Heterocyclic Chem. 1996, 33, 1545-1550.
A. G. M. Barrett, W. W. Doubleday, K. Kasdorf and G. J. Tustin "Stereochemical Elucidation of the Pentacyclopropane
Antifungal Agent FR-900848" J. Org. Chem. 1996, 61, 3280-3288.
A. G. M. Barrett and K. Kasdorf "Total Synthesis of the Antifungal Agent FR-900848" Chem. Commun.
1996, 325-326.
A. G. M. Barrett, K. Kasdorf, G. J. Tustin and D. J. Williams "Determination of the Full Structure and Absolute
Stereochemistry of the Antifungal Agent FR-900848: an X-Ray Crystallographic Study of (1R,3S,4R,
6S,7S,9R,10S,12R)-Quatercyclopropyl-1,12-dimethanediyl Di-4-bromo-benzoate" J.
Chem. Soc., Chem. Commun. 1995, 1143-1144.
A. G. M. Barrett, K. Kasdorf, A. J. P. White and D. J. Williams "Approaches to the Assembly of the Antifungal Agent
FR-900848: Determination of the Geometry of the DicyclopropyletheneUnit and an X-Ray Crystallographic Study of
(1R,2S)-1,2-Bis[(1S,2S)-2-methylcyclopropyl]-1,2-ethanediyl 3,5-Dinitroben--zoate" J. Chem. Soc.,
Chem. Commun. 1995, 649-650.
A. G. M. Barrett, W. W. Doubleday, K. Kasdorf, G. J. Tustin, A. J. P. White and D. J. Williams "Approaches to
the Assembly of the Antifungal Agent FR-900848: Studies on the Synthesis of C2 Symmetric Tetracyclopropane Derivatives
and an X-Ray Crystallographic Study of (1R,3S,
4S,6R)-Bicyclopropyl-1,6-di-{2-[(4R,5R)-di-(isopropyloxycarbonyl)-1,3-dioxolane]}
" J. Chem. Soc., Chem. Commun. 1995, 407-408.
A. G. M. Barrett, K. Kasdorf and D. J. Williams "Approaches to the Assembly of the Antifungal Agent FR-900848:
Studies on Double Asymmetric Cyclopropanation and an X-Ray Cystallographic Study of
(1R,2R)-1,2-Bis-[(1S,2S)-2-methylcyclopropyl]-1,2-ethanediyl 3,5-Dinitrobenzoate"
J. Chem. Soc., Chem. Commun. 1994, 1781-1782.
P. Singh, S. G. Levine and K. Kasdorf "Structures of
4b-(Nitromethyl)-2a, 6a-diphenyl-4a-piperidinol and
4b-(Nitromethyl)-2b,6b-diphenyl-4a-piperidinol" Acta
Cryst. Sect. C 1992, 48, 1996-20
P. Singh, S. G. Levine and K. Kasdorf "Structure of 2,6-Diphenyl-4-piperidone,"
Acta Cryst. Sect. C 1990, 46, 2469-2470.
Patents:
Dennis C. Liotta, Krista Kasdorf, Dawei Zhang, Neysa Nevins and James P. Snyder
"Serine Protease Inhibitors" U.S. Patent Application, April 14, 1997.
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